QUOTE (Pants Rowland @ Oct 16, 2009 -> 11:27 AM)
One thing I do find helpful to end these types of emails is to go to Snopes, fact check the message and paste the correct information into a reply just to whoever sent it to you. Include a very polite but pointed message letting them know you appreciate them thinking of you but emails like this are typically incorrect 99.9% of the time and only serve to cause all the problems already articulated in this thread. Let them know you are interested in hearing about them rather than some Kenyan boy born with a goat's tail and see if they want to get together and catch up. People really appreciate the tip and change their habits accordingly.
Otherwise, if you hate the person, do the fact check, paste in a reply, but do a "reply all" and embarrass them publicly for spreading false information, being too stupid to realize it, and burdening their friends not only with wasted time and a clogged inbox, but potentially more spam via emailing lists. You will be spreading the message to more people, stopping that particular person from ever sending anything to anyone again, and, since you hate them anyway, you will never have to speak with them again.
Both options have been very effective for me.
I've done the latter to a couple of people that annoy the s*** out of me.