I must say, aside from the obvious, my favorite Jim Thome moment was in 2006, when we were ripping the Cardinals apart for the first two games of a three game set at the Cell. I was at all three games (dad is a huge Cards fan).
The third game was different (and I went with a buddy instead of my old man). It was 0-0, in the 7th I think, and the Sox hadn't gotten a hit, let alone a run. Thome comes up, and just RIPS one to right field. f***ing gonzo.
Sox win 1-0 on that, their only hit of the ballgame.
Also, I'll never forget Spring Training 2006, and Thome's slow start, but then he hit like 8 bombs in the last 8 games and carried it into the season on a huge hotstreak. I was certain he'd park 50. Unfortunately, he got injured right around the All-Star Game and wasn't the same from there on out, which really hurt the Sox as they slid to third place. Still 42 bombs was a nice debut season from the big guy.