1. Game 1 of the ALDS versus Boston(by FAR the loudest the Cell has ever been, not even close)
2. Game two of the ALCS versus Anaheim
3. Game 1 of the World Series
4. Buehrle's No-no
Five would be a tie between JD's walk-off against the Angels, 2006 Opening Day, Valentin's walk-off against the Cubs(me and Great Scott have been to a lot of the same games...), Carlos Lee's walk-off granny against the Cubs, and watching Jose Valentin hit for the Natural cycle.
Game 3 will hopefully make the list.