Yes, I would say that is entirely possible. They gave up 14 runs, can they cut that in half? Let's look at the numbers and all the red flags.
First and foremost, the White Sox's strategy coming into this series was to be extremely well rested, and they were willing to sacrifice seeding and matchups for it. This strategy did not work. Despite their guys being better rested, they were outperformed in every aspect of the game - pitching, hitting, and defense, and teams that did not have the last 2 months to coast are still playing in the postseason. This should absolutely call into question the strategy of trying to be the best rested team rather than pushing harder for seeding down the stretch. Is it a coincidence that pitchers who got extra rest and fewer innings down the stretch struggled to find the strike zone, or was that rust? There's an old joke in some other fields that a strategy "Cannot fail, it can only be failed" - resting guys extra down the stretch shouldn't be some topic that we can never question when we just watched it not work.
Second, Giolito and Rodon gave up 4 runs on red flag plays. Giolito should not have been allowed to get in trouble once it got to the 5th inning, he was pulled at least 1 batter too late, and that was a concern. Worse, no one has said that "Bringing in Crochet on a back to back outing" was a good idea, literally everyone assumed he was unavailable after pitching the night before, and some people said it was a shame to use him in a game that was out of reach since it meant he couldn't pitch in game 2. Could that knock 2 runs off? Similarly, Rodon gave everything he had through the Alvarez at bat, and when he tried to throw a high fastball by Correa on the third pitch, he couldn't get it high or hard enough. Yes, pitch calling there was confusing, but overall Rodon should not have been in that game at that point. The rule for both of those guys should have been "Empty the tank, and we will not let you lose this game". That's potentially 4 runs.
Finally, Lance Lynn should not have pitched on the road in Houston. This was the most obvious red flag coming into this series, it was obvious after his outing in June. Whether that means moving him to game 3 or actually going for Home Field Advantage, he had a career ERA over 5 in Houston and an ERA in the low 3s against the same team at home. Furthermore, Lynn himself complained afterwards about the game plan, which involved him throwing like Lance Lynn always does against a team that hits fastballs well. Could that cut a couple runs off what Lynn gave up, or gotten a few more innings out of him? I fully believe he has a better game if he pitched at home, and it sure seems like changing something up against this team would have benefited him.
Cutting 6 or 7 runs off what they gave up - certainly possible, and that's without considering other things like defensive positioning, which we also saw to be important. Every one of those had a red flag saying "do not let this guy lose this way", and that's exactly how they lost. There are other confusing moves throughout this series - having Kopech come into game 4 less than 48 hours after he threw a 50 pitch outing still seems inexplicably bizarre.
The 2 pitchers I'm ok with criticizing and saying "They needed to be better" are Cease and Kimbrel. Even though Kimbrel got hurt by the coaching staff also by moving Leury to RF, both of those guys were put out there in situations where they needed to be better and they weren't.